In High Blood Pressure Chlorthalidone And Hydrochlorothiazide Have A Similar Effect On Mace
A suggestion of benefit from chlorthalidone in patients with prior stroke/MI is difficult to interpret, Areef Ishani says. CHICAGO, IL—Chlorothalidone does not reduce major adverse cardiovascular events compared with hydrochlorothiazide in older, predominantly male military veterans with hypertension, according to the randomized Diuretic Comparison Program (DCP). Through a median follow-up of 2.4 years, the primary outcome MACE—complex stroke, MI, hospitalization for heart failure, unstable angina leading to urgent coronary revascularization, or noncancer death—occurred in approximately 10% of patients in each arm study (HR 1....